ICBB2017|第六届国际生物技术与生物工程学术会议

2017国际前沿生物医学与生物医学工程学术会议(ICABBE2017)

第六届国际生物技术与生物工程学术会议(6th ICBB)

2017年9月26-28日 德国·奥芬堡

大会报告

   

大会报告形式

  会议包括大会特邀报告、口头报告和墙报(张贴报告)等形式交流。无论是口头报告还是墙报展示,均属大会同等学术交流,大会将颁发参会交流证书。如需报告,请在参会回执中注明 “口头报告”或“墙报”的字样。会议将统一安排墙报的参观时间,作者自行喷绘打印后(A0尺寸,90cmX110cm)于报到当日提交,根据大会安排,在规定的时间到会自行张贴,会务会为您提供必要的工具(胶带、图钉等)。

如何成为报告人

  除了邀请的特邀、主题报告人外,大会委员会还将从参会者提交的摘要中选取合适的作者,作为主题报告或口头报告人。请有意在大会做报告的学者通过注册页面提交摘要和学术简历。

大会报告人

已确认报告人如下,更多报告人将在确认后尽快公布。


Prof. Dr. Karl Kunzelmann
德国雷根斯堡大学教授
研究领域: His group is interested in the process of electrolyte transport that takes place in epithelial tissues from kidney, airways and intestine. Ion transport in these tissues controls blood pressure (kidney), mucociliary clearance (airways) and intestinal transport (colon). We have a particular interest in the function, regulation and biophysical properties of ion channels, particularly the cystic fibrosis transmembrane conductance regulator (CFTR) and anoctamins (TMEM16) 
He has published 187 Original papers in peer reviewed Journals, 42 Reviews in peer reviewed Journals, 25 Contributions to books. H-index: 57.
报告题目: Anoctamins, a common protein family with unusual properties and broad biological relevance

Prof. Alexander M. Kulminski
美国杜克大学教授
研究领域: Biological physics; Bio-demography; Health sciences and aging; Genetics and genomics
发表了超过120篇文章,做过超过140场国际会议报告。
报告题目: Genome-wide meta-analysis leveraging genetic heterogeneity identified abundant associations with multiple age-related phenotypes
 
Prof. Dr. Choi Seong Soo
韩国鲜文大学、韩国成均馆大学纳米生物科学研究中心主任
研究领域: Nanofabrication of Plasmonic Nanopore for single molecule analysis, Characterization and Fabrication of Nanostructure.
发表超过170篇论文。
报告题目: Towards the Plasmonic Nanopore on Au-C binary mixture membrane for Next Generation Nanobio Sensor

高殿帅 教授/博士
徐州医学院神经生物学与细胞生物学研究所
研究领域:Currently, his researches focus on GDNF receptors and GDNF function in glioma and PD. His researches involve many subjects comprising of migration and proliferation of glioma cells, epigenetic mechanism, dopaminergic neurons. He also has 4 patents on his researches. Edited books like “Etiology and pathophysiology of Parkinson’s disease” and “Striatum: Anatomy, Functions and Role in Disease”. Editor of Chinese Journal of Neuroanatomy, reviewer of Neuroscience Letter, Evaluation expert of the national natural science research fund project and China postdoctoral fund project. He has a B.S. in clinical Medicine, M.S. in Neuro-anatomy, and Ph.D. in Neurobiology. 
报告题目: Epigenetic modifications promote abnormally high transcription of GDNF gene in glioma cells

Prof. Dr. Jürgen Rühe
德国弗莱堡大学教授
He was the Managing Director of the Department of Microsystems Engineering and the founding director of the Freiburg Institute for Advanced Studies (FRIAS). From 2006 to 2014 he served as Vice Rector for Internationalization and Technology Transfer of the University of Freiburg.
研究领域:
Polymers at interfaces, metamaterials, surface modification, biomedical surfaces, micro- and nanostructuring of surfaces, anti-(bio)fouling strategies, biosensors, surface analysis.
报告题目: Engineered Biointerfaces through Tailormade Surface-attached Polymer Networks – From to new diagnostic tools to implantable materials

Dr. Rina Rosin-Arbesfeld
以色列特拉维夫大学赛克勒医学院临床微生物学和免疫学系
研究领域:Rosin-Arbesfeld's research group have been involved in developing a novel treatment strategy based on mutation stop-codon read-through in key genes. This read-through platform is currently used to develop specific drugs against spinal muscular atrophy (SMA) by BioBlast Pharma and is in clinical trials as a treatment for patients suffering from Familial Adenomatous Polyposis (FAP).
In other aspects of her work, Dr. Rosin-Arbesfeld is focusing of different aspects of the Wnt pathway and is currently establishing methods for prolonging the life span of Red Blood Cells (RBCs).
报告题目: A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents.
  
Prof. Dr. Tatsuo Omata
日本名古屋大学生物农业研究生院
He has been working on CO2 and nitrate assimilation of cyanobacteria and published more than 90 papers in reputed journals.
研究领域:His research at the laboratory aims at better understanding the ways plants and algae acquire energy, carbon, and nitrogen. It seeks to understand the events involved, in terms of basic mechanism, and to discover the ways they are integrated and regulated so as to determine the response of the photosynthetic organisms to different physical and chemical environments.
The research projects focus on the areas of plant biochemistry, molecular biology, and physiology, etc.
报告题目: Importance of the “Milking” strategy for sustainable production of biofuels using photosynthetic microorganisms

Prof. João Lúcio 
巴西卡洛斯联邦大学农学院遗传学系
He is the member of editorial board from 14 international peer-review journals, and the reviewer of 44 internationaljournals like Plos One, Current Microbiology, Biocontrol and other researchjournals.
研究领域: Microbial genetics, biodiversity, microbiology
发表了超过 240 篇文章,H指数为 46.
报告题目: The diversity of citrus endophytic bacteria and their interactions with Xylella fastidiosa and host plants

Dr. Johanna Witzell
瑞典农业科学大学副教授
研究领域:Her research interests are forest damages, tree resistance and stress responses (with special interest in phenolic defensive compounds), functional traits of fungal endophytes of trees, Dutch elm disease and invasive Phytophthora-species.
报告题目: Phenotype MicroArrays reveal new details of endophytic life style
 
Prof. Paulo Teixeira Lacava
巴西卡洛斯联邦大学生物科学与健康中心
研究领域:Has experience in Applied and Molecular Microbiology, focusing on Molecular Plant Microbes Interaction; acting on the following subjects: a) Role of Microorganisms in Crop Protection: Plant Growth Promotion and Biological Control; b) Biological Control of Insect-Pest and Diseases by Microorganisms; c) Endophytic Microorganisms: A Biotechnological Potential in Agrobiology System and d) Plant Growth-Promoting Rhizobacteria (PGPR).
报告题目: Genetic manipulation of endophytic bacteria for symbiotic control of Xylella fastidiosa, causal agent of citrus variegated chlorosis

Prof. Jiri Jan
捷克布尔诺科技大学
Prof. Jan is a senior member of IEEE and a member of EURASIP. He was or is serving as Associate Editor for several international journals and served as a programme committee member or session organiser of many international conferences, a.o. IEEE – EMBC, IEEE – ICASSP and ISBI, Eurasip - EUSIPCO, IFMBE, WOC and others. 
研究领域:His present research interests are in the area of medical image data processing and analysis, concerning namely multimodal image fusion, diagnostic feature analysis and image reconstruction from non-standard tomographic data. 
报告题目:Spine lesion analysis in 3D CT data – reporting on research progress 

Prof. Dr. Silvia Mittler
加拿大西安大略大学
Since September 2003 I have been a member of the faculty in the Department of Physics and Astronomy at Western. I am running the Laboartory for Photonics of Surfaces and Interfeces. I was holding a Tier I Canada Reaserch Chair for 7 years (2004-2011). In September 2010 I have received an Award of Appreciation from Sciencetech Inc., London, Ontario. 
研究领域:My research was selected various times for an issue of the Virtual Journal of Biological Physics Research (published by the American Physical Society and the American Institute of Physics) which publishes articles from participating publishers, covering a focused area of frontier research.
报告题目:Waveguide Evanescent Field Microscopies: WEFF and WEFS microscopy

Prof. Luca Mesin
意大利都灵理工大学
Associate Professor in Biomedical Engineering at Politecnico di Torino, Italy. He is the head of the research group on Mathematical Biology & Physiology.
研究领域:His research activities are devoted to the processing of signals or images extracted from biological and physiological systems and to the development of mathematical models for the interpretation of the recorded data. Applications are mainly focused on the investigation of biological systems or on the development of new biomedical tools. Recent works concern the simulation of spiral waves using a model of electromechanical coupling in the heart, the investigation of the central venous pressure, the processing of multiple data reflecting the responses of the Autonomous Nervous System and the simulation and processing of bioelectric signals. 
报告题目:Reduction of Crosstalk in Surface Electromyogram by Optimal Spatio-Temporal Filtering
 
Dr. Oliver Faude
瑞士巴塞尔大学
研究领域:His research focuses on Sports Medicine, including Sports Medicine, Exercise Science, Sports Science, Biomechanics, Exercise Physiology, Sports Injuries, Exercise Performance, Nutrition and Exercise Performance. 
多本期刊的编委与评审人,发表超过130篇文章,H指数为22,总被引2281
 
David D. McFadden, M.D.
Mayo Clinic, U.S.A
The research of David D. McFadden, M.D., focuses on alternative and complementary methods and treatments for smoking cessation.
研究领域:Dr. McFadden is particularly interested in exploring how a person's mind, attitudes and beliefs impact nicotine addiction. He is exploring alternative acupuncture protocols and spirituality as potential treatments for nicotine addiction. Future studies may involve herbal remedies, Tai Qi and Qi Gung.

已接收摘要(Oral和Poster)

  下列是大会已接收的摘要列表。列表定期更新,仅注册后的报告才会排入到会议日程、会议手册中。(最后更新日期:2017年8月31日)
1,   Abdurraouf ZAET,   D-Cateslytin, A new Potent Antimicrobial Peptide for Therapeutic Application 
2,   Akbar Esmaeili,   Optimization and characterization of coaxial electrospun sodium carboxymethyl cellulose-graft-methyl acrylate/poly(ethylene oxide) nanofibers for drug-delivery applications
3,   Alexander M. Kulminski,   Genome-wide meta-analysis leveraging genetic heterogeneity identified abundant associations with multiple age-related phenotypes
4,   Ali Karimi ,   In vitro antioxidant and antiproliferativeeffects of crude hydroalcoholic extract of Pomegranate (Punicagranatum L.) peeland subsequent fractions on AGS cell line
5,   Amir Roushdy Ali,   Novel design of electrical sensing interface for prosthetic limbs using optical micro cavities
6,   Anna Varizhuk,   The many facets of G4 DNA structures
7,   Ardeshir Hesampour Mahalati,   Catalytic efficiency and thermostability improvement of phytase through rational mutagenesis for enzyme Industrial application
8,   Arian Ansardamavandi,   Effects of Substrate Stiffness on Morphological Alternations, Proliferation, Motility and Genes Expression in Breast Cell Lines with Different Invasiveness
9,   Arti Taneja,   Automated Cell Nuclei Segmentation in Overlapping Cervical Images Using Deep Learning Model
10,   Asma Karim,   Genetic diversity between Cirrhinus mrigala from two different habitats (Farm and River) on the basis of CO1 gene sequences
11,   Baole Zhang,   Epigenetic mechanism of abnormally high GDNF transcription in glioma cells
12,   Bumgeun Choi,   Low Fluid Shear Stress induces the differentiation of human bone-derived mesenchymal stem cells under rocking platform
13,   Carlos Laino,   PHARMACEUTICAL INNOVATION IN THE TREATMENT OF PAIN:  COMBINATION OF MORPHINE WITH OMEGA-3 FATTY ACIDS
14,   Cheol Song,   Diffuse speckle contrast analysis for deep tissue flow monitoring
15,   Cynthia Machado Cascabulho,   Chemotaxis and Immunoregulatory Function of Cardiac T Cells in Dystrophin-Deficient Mice
16,   David D McFadden,   Trial of intensive acupuncture for smoking cessation: a pilot study
17,   Dianshuai Gao,   Epigenetic modifications promote abnormally high transcription of GDNF gene in glioma cells
18,   Dong-An Wang,   Development of an in vitro rheumatoid arthritis (RA) model and its application in drug testing
19,   Eglė Lastauskienė,   Electroporation in combination with weak organic acids is suitable for the biocontrol of the skin colonizing yeasts
20,   Elsayed Ibrahim Imam Morgan,   Novel techniques for high resolution magnetic field detection using WGM based sensor
21,   Farshid Talat,   FACTORES AFECTING SYNONYMOUS CODON USAGE BIAS IN CHLOROPLAST GENOMES OF Gossypium thurberi AND Gossypium arboreum
22,   Florian Ott,   Probing Activity of Immobilized P450BM3
23,   Gen Li,   A Non-invasive Non-contact Continuous Monitoring System of Brain Edema Based on Magnetic Induction Phase Shift and Computer Programming
24,   Grace Mosunmola Adegbola,   Bioremediation of Nutrient Amended Hydrocarbon Contaminated Soil: Influence on Vegetative Properties
25,   Heba Kamal Mohammed Ahmed & Ethar M. Said-Ahmed Ataa-Elmanan,   The biostability of gold nanoparticles for cancer treatment
26,   Herbert Wachtel,   In vitro Analysis of Respimat® Respiratory Drug Delivery in Children
27,   Imam morgan, Amir Roushdy,   Novel techniques for high resolution magnetic field detection using WGM based sensor
28,   Javad Ranjbari,   Enhanced Production of Insulin-like Growth Factor I Protein in Escherichia coli by Optimization of Five Key Factors
29,   Jeff Wright,   Forest Plantation and Harvesting Systems for Eucalyptus Biomass Investments in Florida USA
30,   Jens Tiefenbach,   Zebrafish based small molecule screening identifies idebenone as new PPAR/dual agonist
31,   Jian Li,   Trichomonas vaginalis genome and transc<x>riptome provide insights into Trichomonas gene expansion and evolution
32,   Jiri JAN,   Spine lesion analysis in 3D CT data – reporting on research progress 
34,   João Lúcio Azevedo,   The diversity of citrus endophytic bacteria and their interactions with Xylella fastidiosa and host plants
35,   Johanna Witzell,   Phenotype MicroArrays reveal new details of endophytic life style
36,   Julie Zaworski,   Deinococcus geothermalis genome scale studies to  engineer heterologous metabolic pathways 
37,   Jürgen Rühe,  Engineered Biointerfaces through Tailormade Surface-attached Polymer Networks – From to new diagnostic tools to implantable materials
38,   Kaiyu Wang,   Application Development of Remote EEG Acquisition and Analysis Based on the Intel RealSense Technology
39,   Leila Karimi,   Mn-ferrite superparamagnetic nanoparticles coated by Palmitic Acid Modified Pegylated chitosan as a carrier for anticancer drugs
40,   Luca Mesin,   Reduction of Crosstalk in Surface Electromyogram by Optimal Spatio-Temporal Filtering
41,   Mahmood Ahmed,   Curcumin derivatives: Anti-inflammatory, analgesic, ulcerogenic, cyclooxygenase-2 inhibition and molecular docking studies
42,   Maryam Goodarzi,   Biosensors as a Rapid Method for Detection of Foodborne Pathogenes 
43,   Matthias Rieckher,   Combining Light Sheet Microscopy and Optical Projection Tomography to visualize protein dynamics in small model organisms and spheroid tumors
44,   Maurits Hoonhorst,   Does Transcranial Magnetic Stimulation have an added value to clinical assessment in predicting upper limb function early post-stroke?
45,   Mehdi Najar,   Inflammatory response of bone marrow mesenchymal stromal cells: gene and protein immuno-profiling 
46,   Milena Chraniuk,   Inhalation tests in vitro for Volatile Organic Compounds (VOCs)
47,   Mohamed Hamdy Doweidar,   In-vivo Cell Remote Control: A Mecano-Electro Computational Study
48,   MOHAMED NASEF,   Activation of autophagy by TRAIL Receptors mediates cyto-protection in urothelial cell carcinoma (UCC) lines in vitro
49,   Muhammad Imtiaz Shafiq,   Design and evaluation of CDK4 inhibitors through molecular docking
50,   Muhammad Nauman Aftab,   Cloning, expression and characterization of β-xylanase gene from Thermotoga naphthophila
51,   Nasreen Thebo,   THERAPEUTIC POTENTIAL OF ALMOND (PRUNUS DULCIS.L) SHELL EXTRACT AGAINST  TINEA  INFECTION
52,   Nermeen Mohamed Serag El Din,   Magnetotactic bacteria act as microrobotes for targeting cancer cell therapy
53,   Niranjan Koirala,   Glycosylation and Subsequent Malonylation of Isoflavonoids in E. coli: Strain Development Production and Insights into Future Metabolic Perspectives
54,   Oliver Faude,   Soccer injuries and their prevention in children´s football
55,   Pareenart Sungkeeree,   Removal of toxic phthalate by enzymatic molecular engineering strategies
56,   Paulo Teixeira Lacava,   Genetic manipulation of endophytic bacteria for symbiotic control of Xylella fastidiosa, causal agent of citrus variegated chlorosis
57,   Piotr Zgłobicki,   UV-induced DNA damage repair by known and putative Arabidopsis thaliana photolyases
58,   Plamen Kirilov,   EX-VIVO PERCUTANEOUS ABSORPTION OF ENROFLOXACIN USING LMOG ORGANOGEL AS DRUG DELIVERY SYSTEM
60,   Rina Rosin-Arbesfeld,   A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents.
61,   Roghaye Arezumand,   Selection of high affinity nanobody using calculation of binding score and experimentally confirmation to modulate angiogenesis 
62,   SALIM ATEEG,   CD40-mediated death and cytokine release in human prostate carcinoma cells: a target for inflammatory tumour cell killing
63,   Samin Seddigh,   Conserved Motif Analysis of Mitochondrial Cytochrome b (Cytb) Enzyme in Insects
64,   Sarah Sabir ,   Molecular Characterization of families affected with autosomal recessive primary microcephaly
65,   Seong Soo Choi,   Towards the Plasmonic Nanopore on Au-C binary mixture membrane for Next Generation Nanobio Sensor
66,   Silvia Mittler,   Waveguide Evanescent Field Microscopies: WEFF and WEFS microscopy
67,   Somchart Chokchaitam ,   Visional Pill Identification for Recognizing Two Similar White-Shade Pills under Various Uncontrolled Luminance Intensity
68,   SRINIVASA REDDY RONDA,   A growth inhibitory model with SOx influenced effective growth rate for estimation of algal biomass concentration under flue gas atmosphere
69,   Tatsuo Omata,   Importance of the “Milking” strategy for sustainable production of biofuels using photosynthetic microorganisms
70,   Télesphore Benoît Nguelefack,   Insight into the analgesic effects of some Cameroonian medicinal plants
71,   Tomohiko Utsuki,   Migration Model of Extracellular Fluid in Cerebral Tissue for Future Automatic Control of Brain physiological State
72,   Tushar Kulkarni,   Hand grip force analysis using surface electromygram
73,   Vladimir Kodkin, Galina Yakovleva,   Developing a system for continuous control of the functional status based on recording of electrical potentials and acoustic signals
74,   Yasir Rehman,   Arsenic detoxification and plant growth promotion by purple non-sulfur bacteria 
75,   Yung-Kai LIN,   In situ Polymerizable Hydrogel Incorporated with Specific Pathogen-free Porcine Platelet-Rich Plasma for the Reconstruction of the Corneal Endothelium
76,   Zahra Mohamadzade,   A New Variant of Hotair
77,   Zamarud Shah,   Introduction of Arabidopsis thaliana HsfA1d into potato (Solanum tuberosum L.) enhances thermotolerance
78,   Julie Zaworski,   Deinococcus geothermalis genome scale studies to  engineer heterologous metabolic pathways 
79,   Pauline Dartevelle,   D-Cateslytin: a new antifungal agent for the treatment of oral Candida albicans associated infections
80,   Plamen Kirilov,   EX-VIVO PERCUTANEOUS ABSORPTION OF ENROFLOXACIN USING LMOG ORGANOGEL AS DRUG DELIVERY SYSTEM
81,   Arian Ansardamavandi,   Effects of Substrate Stiffness on Morphological Alternations, Proliferation, Motility and Genes Expression in Breast Cell Lines with Different Invasiveness
82,   Zahra Mohamadzade,   A New Variant of Hotair
83,   Ali Karimi ,   In vitro antioxidant and antiproliferativeeffects of crude hydroalcoholic extract of Pomegranate (Punicagranatum L.) peeland subsequent fractions on AGS cell line
84,   Maurits Hoonhorst ,   Does Transcranial Magnetic Stimulation have an added value to clinical assessment in predicting upper limb function early post-stroke?
85,   Jürgen Hense,   Challenging brain computer interfaces with a modularized real-time software framework 
86,   Arti Taneja,   Automated Cell Nuclei Segmentation in Overlapping Cervical Images Using Deep Learning Model
87,   An-Bang Liu ,   In Vivo Assessment of Endothelial Function in Small Animals Using an Infrared Pulse Detector
88,   Attila Bóta,   Effects of ursolic acid on the structural behaviours of dipalmitoyl lecithin vesicles
89,   Neelima B.Shitole,   A study of cancer diagnosis using image processing and machine learning
90,   Elena Kornienko,   NEW PRODUCERS OF FIBRINOLYTIC AND ANTICOAGULANT ENZYMES AMONG MICROMYCETES 
91,   Alexandra Rozhkova,   "Increase in thermostability of the 1,4--glucanase from Penicillium sp by site-directed mutagenesis
92,   Ivan Zorov,   Improvement of catalytic properties of the endo-1,4--glucanase from Penicillium sp 
93,   Bernard Fioretti,   Silver(I) promotes calcium influx by inward cationic current activation in U251 human cell line
94,   Kyoko Asakura,   Development of the Grip Power Feedback System for Artificial Hand Users 
95,   Masayuki Kobayashi,   A development of the system to display texture of the object for forearm amputee.
96,   Sercan Karav,   Oligosaccharides released from milk glycoproteins are selective growth substrates for infant-associated bifidobacteria
97,   Nadine Moubayed,   Antimicrobial, antioxidant properties and chemical composition of seaweeds collected from Saudi Arabia (Red Sea and Arabian Gulf)
98,   Shigeki Matsunaga,   A simulation study on a Glucose aqueous solution used in a biofuel cell
99,   Vildan Erci,   Measuring nitrate consumption by C. vulgaris using NO3- ion selective electrode (ISE) 
100,  Fatih Erci,   Green synthesis of silver nanoparticles using Thymbra spicata var. spicata L. leaf extract and evaluation of their biological activities
101,  Stephanie Klinghammer,   Sensing platform for simultaneous real-time detection of multiple steroids
102,  Micheale Yifter Weldemichael,   The current status, future prospects transgenic crops and food safety issues associated with foods derived from genetically engineered crops in the case of Africa: a Review
103,  Shayma Ahmed Hussin,   The biostability of gold nanoparticles for cancer treatment
104,  Marziyeh Ranjbar-Mohammadi,   Development of biodegradable electrospun Poly (ε-caprolactone)/gum tragacanth/poly (vinyl alcohol) nanofibrous scaffold for application as skin substitutes
105,  Mohammad Rasti,   Development of a high affinity DNA aptamer against Vascular endothelial growth factor
106,  Farnaz sadat Sotoudegan,   The increase stability of anti-amyloid β single-chain variable fragment (scFv) via self-assembly of amphiphilic block copolymers
107,  Ilke Anac,   Surface Plasmon Resonance/Fluoresence based biosensor for the Detection of Cholera Toxin  
108,  Vassilios Ganatsios,   A novel double-layer immobilised biocatalyst for simulated barrel aging production of sweet wine 
109,  Tadayasu Komura,   "Analysis for Hand and Leg Motion Recognition from Multichannel Surface EEG Using Coherent Analysis
110,  Franco Simini,   DINABANG: Explosive Force Hamstring Rehabilitation Biomechanics Instrument
110,  Franco Simini,   DINABANG: Explosive Force Hamstring Rehabilitation Biomechanics Instrument
112,  Jürgen Hense,   Challenging brain computer interfaces with a modularized real-time software framework
113,  Markus Brudsche,   Simulation of Atrial Septal Occluder Deformations during Cardiac Cycle
114,  Corinna Brenner,   Sizing of cardiac closure systems using CARTO XP
115,  Bruno Ismer,   Av delay optimisation in cardiac resynchronization using surface ecg- proposal from measurements by esopageal left atrial electrogram
116,  Martin Krämer,   Electrical field simulations in cardiac resynchronization therapy and ablation
117,  Marco Schalk,   Heart rhythm model for Simulation in electrophysiological studies and ablation